Start me up, shut me down

You are using a poorly written application, and it needs to be administratively terminated in order to regain control of your computer. Which of these methods can be used to launch the Task Manager?

A) Alt-Shift-Esc

B) Ctrl-Alt-Esc

C) Ctrl-Alt-Shift

D) Ctrl-Shift-Esc

E) Just bang on the keyboard until something happens